daily alcoholic drink no longer advised

Up until recently, I advised people to have a daily drink, as the research (308 people) suggested that if you have a single drink every day, the all-cause mortality was lower.

But more research has been done, pulling together results from nearly half a million people aged 18 to 85, that shows that a daily drink actually increases all-cause mortality, by a huge factor of 1.23.

Oh well – everything that seems too good to be true generally is.

I now need to adjust the good habits section of the book with this sobering (hah!) result.

Jimmy Joy and Huel prices

the last batch of Jimmy Joy that I bought a year back or so is now out of date. time to get more, so I’m looking into the latest prices of Jimmy Joy and the alternatives, in case the market has produced some new interesting companies.

first stop, Jimmy Joy, and I notice they have a new option, “personalised”, which lets you define exactly what goes into the shake. catch: you need to order 1000kg of it. I can’t help but wonder if this is a result of a question I asked them last year. Anyway – their Plenny Shake is €26 for 25 “meals” of 400kcal each. Averaging to 2000kcal per day, that’s €5.20 per day. their other offerings are more expensive, so I’m skipping onto the next.

Huel’s unflavoured/unsweetened offering is €54 for 14,000kcal. that’s €7.72 per day.

Next, we have Soylent. It’s not as obvious what you’re buying in this case. Their pouch cases contain 35 meals consisting of 7 pouches. How many calories is that? not obvious until you read the nutrition label itself. one pouch contains 2000kcal. Okay. So at $60.80 per case (€52.73), that’s €7.54 per day.

Mana is €1.57 per pouch, and each pouch contains 400kcal, so that’s €7.85 per day.

Queal is €7.50 per day. That’s for the vegan version. The non-vegan version is €7 per day, but if you’re going to go to the effort of being careful about your diet, why not also be ethical about it?

I’ll check these again in a few months again and probably revise into a formatted table and add a few more, but that covers the more commonly-known future foods.

Jimmy Joy is by far the cheapest in this comparison, at €5.20 per day for a nutritionally complete diet.

Artificial Pancreas passes clinical trials

A closed-loop insulin monitoring and delivery system has passed a 12-week randomised trial where the patients were free-living – they were not asked to stay in bed or to be careful in any way – just to live their lives as normal.

Closed-loop insulin delivery (“artificial pancreas”) systems work by monitoring insulin levels and adjusting insulin input every few minutes using an algorithm, which results in a much more glucose level than the usual method which is to measure every few hours and adjust by injection.

Using this method, insulin levels are monitored and adjusted even when the person is asleep.

A meta-review earlier this year compared artificial pancreases with other insulin management systems and found that when using an artificial pancreas, the glucose levels were near normal values significantly more than with any other treatment.

Is Gardasil Dangerous? Part 5

Today I’ll look into the statement “I also know that the ingredients L-Histidine and Polysorbate 80 piggyback the aluminium adjuvant (microsplinters) across the blood/brain barrier where they lodge permanently in the brain tissue. Those ingredients also strip the myelin coating off nerve cells and cause loss to varying degrees of nerve-cell signal transmission. This is what causes loss of sensation in the extremities reported widely.”

part 1 | part 2 | part 3 | part 4 | part 5

The first thing I did was to search and see if there are any references at all online for “adjuvant microsplinters”. I found literally zero pages that had the two words on the same page. Within a few days, I guess this article will be the only one.

Before I get started, there is a misunderstanding here – even if L-Histidine, Polysorbate 80 and the adjuvant were to get through the blood brain barrier together, it would not be the histidine and P80 piggy-backing the adjuvant. It would be the adjuvant and the histidine piggybacking the P80. Polysorbate 80 is a known “key” to the blood-brain barrier door.

L-Histidine

I already discussed L-Histidine in general, but this statement specifically states that L-Histidine lodges permanently in brain tissue, strips myelin from nerves and causes loss of sensation. Heavy words. L-Histidine (also known as Histidine) does not do any of this.

First off, it is already in the brain. Histidine is a precuror molecule to histamine, which is a neurotransmitter. You actually need histidine in your brain for it to function.

If your brain doesn’t get histidine, this can cause anxiety.

If you increase the amount of histidine in your brain, it can actually counteract fatigue and make you more alert and quicker at thinking.

To be afraid of having L-Histidine in your brain is like being afraid of having nerves in your brain.

To say that L-Histidine can “strip the myelin off nerve cells” is actually the complete opposite of what it does! “Histidine is a semi-essential amino acid (children should obtain it from food) needed in humans for growth and tissue repair, Histidine is important for maintenance of myelin sheaths that protect nerve cells and is metabolized to the neurotransmitter histamine. Histamines play many roles in immunity, gastric secretion, and sexual functions. Histidine is also required for blood cell manufacture and protects tissues against damage caused by radiation and heavy metals.”

I found a paper from 1973 where rabbits were injected with doses varying from 62-1500 mg/kg, straight into the brain. No side-effects were noted. The histamine content of the brain rose as the histidine was converted, but there were not side-effects.

The equivalent dosages here in a 70kg human are 4.34g to 105g. Straight into the brain. With no side-effects. Gardasil only has 0.78mg of histadine. That’s 134615 times smaller than 105g. The L-Histidine in Gardasil is not dangerous, either to the body, or to the brain.

Polysorbate 80

Polysorbate 80 is also known as Tween-80 (or P80). As already discussed, it is an emulsifier that is commonly used in food. But for this article, we are looking at what effect it has on the brain.

Tween 80 can be used to help deliver drugs to the brain, as it acts kind of like someone carrying a box in through a door – you can imagine them opening the door with a hand, then pushing the door open while backing in with the box. In this case, the door is the blood-brain barrier (BBB), and the box is the drug payload.

The BBB’s “door” is hard to open. Even though P80 can open the door, it still takes a certain concentration of it to do so. That concentration has been measured as 3mg/kg (3mg of P80 per 1kg of body weight)

P80 causes brain-blood barrier disturbance (it opens the door) at a rate of 3mg/kg. In a 70kg human, you would need 210mg. Gardasil contains 0.05mg of P80. That’s 4200 times too small. The P80 in Gardasil is not enough to open the blood brain barrier.

But, let’s assume it somehow got through and is now in the brain itself. What effect does P80 have on the brain?

Most research into P80 and the brain has to do with whatever P80 is helping across the BBB. I could not find anything that was specifically about P80 and not its payload. Even the anti-vax websites all talked about the payload and not P80 itself. And I certainly couldn’t find anything suggesting that Polysorbate 80 had any effect at all on myelin.

Aluminium Hydroxyphosphate Sulfate

The aluminium (Al) in Gardasil is in the form Amorphous Aluminum Hydroxyphosphate Sulfate.

A lot of the scare stories I saw on anti-vax websites about the aluminium in Gardasil are about aluminium oxyhydroxide. Aluminium oxyhydroxide and aluminum hydrophosphate are not the same. They don’t act the same. They’re not even the same size!

Aluminium oxyhydroxide particles tend to form clumps about 0.96μm in size, while Aluminium hydrophosphate particles clump at around 1.31μm. The clumps are always globular in shape, never “microsplinter” shaped. See the images here for example.

A comparative study of the ultimate fate of aluminium-based adjuvants found that High loading of aluminium oxyhydroxide in the cytoplasm of THP-1 cells without immediate cytotoxicity might predispose this form of aluminium adjuvant to its subsequent transport throughout the body including access to the brain”. That’s aluminium oxyhydroxide. Not hydrophosphate. They are different adjuvants.

When injections of the various adjuvants were tested, it was found that “Mass spectrometry analyses of digested tissues identified higher aluminium concentrations in the kidneys with the lowest concentration found in the brain. The dissolution of Adju-Phos® however, was found to be more rapid than that for Alhydrogel® with higher Al concentrations noted in the surrounding tissues, probably owing to the amorphous nature of the former”, and “elevated Al concentrations were found in both urine and tissue samples”. In other words, no microsplinters. The hydrophosphate form of adjuvant broken down quite quickly and was dissolved out into surrounding tissues and eventually pissed out.

A paper that I see frequently referenced on anti-vax websites is Biopersistence and Brain Translocation of Aluminum Adjuvants of Vaccines. The article mentions that Alum crystals come in mostly three forms, oxyhydroxide/hydroxyphosphate/phosphate, but writes as if they are all the same. In fact, the first three words of the paper “Aluminum oxyhydroxide (alum)” mean that when he writes “alum”, he is specifically talking about the oxyhydroxide form, not the others.

The idea that aluminium can “lodge permanently in the brain tissue” is true. It’s known to happen even in the absence of vaccines. There is no single average density of aluminium to brain matter, as the amount increases with age.

Too much aluminium in the brain is linked to various conditions, such as Alzheimers (2.98 μg/g) in a case where the aluminium was accumulated over time, or death (0.97 μg/g) when it’s accumulated all at once. It has also been associated with autism (3-8 μg/g). This document has a number of other figures: “Alzheimer’s disease (up to 11.5 μg/g dry wt); dialysis encephalopathy (up to 14.1 μg/g dry wt); congophilic amyloid angiopathy (up to 23.0 μg/g dry wt); and various
aluminium-related encephalopathies (up to 47.4 μg/g dry wt).”

That last document had the phrase “piggy-back” in it, by the way, so I wonder if that’s where the idea of P80 and histidine piggybacking on Al came from? In this case, it says “Under conditions of chronic exposure to aluminium, the selectivity of the blood-brain barrier may not be seriously compromised, and aluminium will gain entry to the brain by piggy-backing upon normal transport mechanisms as well as through more indirect processes such as residual leakiness and fluid phase endocytosis”. “Chronic” is very important there.

It is also known that aluminium can help cause oxidative effects on myelin, so that part is true as well.

But how much aluminium is in the brain already, and how much does a shot of Gardasil add to that?

60 brains were donated to a study on aging. The average Al load of the brains was 1.05 μg/g. As these were all otherwise healthy (apart from the being dead bit) brains of people that died at an advanced age, 1.05 μg/g can be considered the “normal” density of aluminium to brain.

The average human brain weighs about 1.3kg. That means there is about 1.365mg of aluminium in the brain of an aged adult human.

The chemical formula for Aluminum Hydroxyphosphate Sulfate is AlHO9PS-3. The relative weights of the chemicals are Al=26.981, H=1.007, Oxygen=15.999(*9), Phosphorous=30.973, Sulphur=32.059(*3), so there’s a ratio 26.981:299.129 aluminium to aluminium hydrophosphate sulfate.

There’s 225μg of Aluminum Hydroxyphosphate Sulfate in Gardasil, which contains 20.29μg of aluminium.

20.29μg is 67.27 times smaller than 1.365. So even if you were to inject the entire Gardasil dose straight into the brain, you would increase the brain’s aluminium content by only 1.49%.

Of course, when you vaccinate yourself, the contents of the vaccine doesn’t just automatically go straight to the brain. It spreads through the blood-stream to the whole of the body before being mostly pissed straight out.

If you divide the weight of the brain into 70kg, you get 53.85. That means that you can expect at most 1/53.85th of the vaccine to get through the blood-brain-barrier (assuming that 100% of the vaccine that ends up knocking at the door gets in). That means the amount of aluminium in the brain goes up by even a smaller amount. Instead of increasing by 20.29μg, we increase by 0.38μg, or 0.027%.

The idea that increasing the existing aluminium load of the brain by 0.027% will suddenly cause it to strip myelin and cause loss of sensation, etc – that’s absurd.

In the next article, I’ll tackle this: “It can and does affect some people to a greater degree by stopping the autonomic nervous system from working properly, leading to respiratory and cardiac system failure and death”

Is Gardasil Dangerous? Part 4

Today I’ll tackle this statement: “the rats used during development and testing developed reproductive problems ranging from early onset menopause and ovary destruction, to total and permanent reproductive system failure.”

part 1 | part 2 | part 3 | part 4 | part 5

A report of three girls with premature ovarian insufficiency was submitted in 2014 in Australia. The document is impressive, and at first glance seems to condemn Gardasil, but the authors themselves say that the results are inconclusive for many reasons (see Conclusion section).

The document is useful to this article, though, because it details Gardasil’s preclinical trials, including the rat trials alluded to in the statement.

In the HPV fertility safety tests, there were 4 groups of Sprague-Dawley rats – control with phosphate-buffered saline, control with the standard Gardasil buffer, vaccine group given vaccine after mating, vaccine group given vaccine weeks before mating. The rats were given the full human dose. That is equivalent to a human receiving 200 doses at once.

The fecundity index for rats that received the vaccine weeks before mating was 95%, which is actually 2% higher than the average fecundity index for Sprague-Dawley rats, which is typically 93% (+/- 9.88%).

This means that there was no effect at all on the test rats. No “early onset menopause”, no “ovary destruction”, no “total and permanent reproductive system failure”. In fact, the rats gave birth normally, with no surprises at all.

The resulting paper, titled “Lack of effects on fertility and developmental toxicity of a quadrivalent HPV vaccine in Sprague-Dawley rats, stated that “There were no unscheduled deaths during the study. There was no evidence of toxicity in the F0 females given either MAA or vaccine. There were no effects on the fertility or reproductive performance of the F0 females. There was no evidence of developmental toxicity to the F1 generation, including fetal body weight and morphology, postnatal growth and development, behavior, and reproductive performance. […] These results demonstrate that this quadrivalent HPV vaccine had no detectable adverse effects in either the treated F0 female rats or the F1 generation”.

In another test, the vaccine was tested specifically on the fertility of male rats, with similar results. 30 rats were given full human doses of Gardasil. The results showed that there was no effect on either reproduction, or on life expectancy. “There were no unscheduled deaths during the study and no evidence of toxicity in vaccine-treated male rats. The vaccine induced a specific antibody response to the 4 HPV types after each injection. There were no effects on the cesarean-section parameters of females or reproductive parameters of the cohabited male rats, including histomorphology of testes and epididymis, sperm count, and sperm motility.”

Again, Gardasil is safe. It was tested at 200-times dosage in rats with no effect at all, so the statement I was given was wrong.

Tomorrow I’ll look into the statement “I also know that the ingredients L-Histidine and Polysorbate 80 piggyback the aluminium adjuvant (microsplinters) across the blood/brain barrier where they lodge permanently in the brain tissue. Those ingredients also strip the myelin coating off nerve cells and cause loss to varying degrees of nerve-cell signal transmission. This is what causes loss of sensation in the extremities reported widely.”

Is Gardasil Dangerous? Part 3

I’m still not finished looking into the ingredients of Gardisil, so let’s continue.

part 1 | part 2 | part 3 | part 4 | part 5

From the FDA: “Each 0.5-mL dose of the vaccine contains approximately 225 mcg of aluminum (as Amorphous Aluminum Hydroxyphosphate Sulfate adjuvant), 9.56 mg of sodium chloride, 0.78 mg of L-histidine, 50 mcg of polysorbate 80, 35 mcg of sodium borate, <7 mcg yeast protein/dose, and water for injection.“.

The remaining ingredients to look at are 35μg of sodium borate, 50μg of polysorbate 80, and water for injection. I think we can safely ignore the water…

Sodium Borate

We’ve already discussed how the individual chemicals in a compound really don’t matter all that much. Otherwise, we would all explode when we get warm, because hydrogen and oxygen are extremely flammable. Sodium borate contains sodium, oxygen, and boron. Sodium is an explosive metal, oxygen is an extremely reactive gas that can erode metal or burn right through it, and boron can be used as a fuel in aneutronic fusion reactors.

Sodium borate is also known as borax. Its most common uses are as anti-fungal treatments, fire retardents, insecticides, and as an ingredient in cosmetics and detergents.

It’s also a food additive, E285, which is banned in a few countries because when consumed in “large quantities”, it can lead to liver cancer. Large quantities. Remember that consuming salt in large quantities also has effects, and you can even die from drinking too much water. Let’s deal in hard numbers, not vagueries.

Borax is measured as having an LD50 of 2.66g/kg in rats, which is between THC (1.27g/kg) and salt (3g/kg). 2.66g/kg is the same as 186.2g/70kg, so if you’re 70kg in weight, 186.2g is 50% likely to kill you. Don’t eat 186.2g of sodium borate.

Borax is used as an insecticide with no restrictions in the US, because the EPA has found in multiple examinations that “because they are of low toxicity and occur naturally, boric acid and its sodium salts should be exempted from the requirement of a tolerance (maximum residue limit) for all raw agricultural commodities”.

It has been found to inhibit the growth of tumours, as demonstrated in this paper where the concentration of Borax was related strongly to the destruction of HepG2 cells (human liver cancer cells).

There is no measurement of what is a safe amount of sodium borate to consume in a day, but because its LD50 is so similar to salt, we can use that as a guesstimate. sodium borate’s LD50 is 0.89 times salt’s, so we can say for the purposes of this argument that the RDI is 0.89 times salt’s RDI (2.3mg per day), or 2.047mg.

Gardasil contains 0.035mg of sodium borate, which is 58.5 times smaller than 2.047mg (our calculated RDI) and 5,320,000 times smaller than 186.2g.

The amount of sodium borate in Gardasil is safe.

Polysorbate 80

Polysorbate 80 is a surfactant (lowers surface tension between liquids) and an emulsifier (a substance that “gels” things together).

Polysorbate 80 is a food additive (E433) that you will find in ice creams and deserts, wine, soups, chewing gums, food supplements, medical supplements, sauces.

A study in 2008 discovered that if you feed a pregnant rat 16.783 ml/kg/day polysorbate 80, the offspring may be smaller. That’s the equivalent in a human of eating 1.3kg of polysorbate 80 every day. If you are pregnant, don’t do that.

People eat an average of 100mg of polysorbate 80 every day.

I really can’t find anything dangerous about this stuff. I can’t find anything about anyone ever dying from eating polysorbate 80. The only recorded effect it seems to have on humans is that if you have Crohn’s disease, it might give you a tummy ache.

There’s 50μg of polysorbate 80 in Gardasil. You consume 100mg of it every day. That means you are already consuming 2000 times as much polysorbate 80 in your normal diet as you will get from Gardasil.

Conclusion

I was told that the ingredients in Gardasil are very scary. After researching them, I’m really struggling to find out what the fuss is. Every one of them is perfectly safe. In most cases, you already ingest much more of the ingredient in your daily life than you will get from Gardasil.

In the next article, I will look at the next portion of the post that originally started this, where I was told that “the rats used during development and testing developed reproductive problems ranging from early onset menopause and ovary destruction, to total and permanent reproductive system failure.”

UBX0101/Navitoclax update

I haven’t looked in on this in a while, but there are some interesting new developments.

UBX0101 (also known as Navitoclax, or ABT-263) is a drug that is used currently in anti-cancer treatments.

It is also a senolytic, meaning that it can be used to destroy senescent cells in the body (the cells that make you old).

When I last looked into UBX0101, no human trials had yet been done on the senolytic aspect. This year, UBX0101 became the first drug to go into human trial for specifically its senolytic aspects.

Announced in June 2018, the trial recruited sufferers of osteoarthritis of the knee.

In the trial, the patients are injected at the site of the osteoarthritis with UBX0101, which then selectively targets the senescent cells that are the cause of the complaint (through their inflammatory effect), and destroys them.

The trial is not due to complete until November (in two months), so we don’t know for sure how it’s going, but based on how the market is responding, there is really good news coming.

Is Gardasil Dangerous? Part 2

Continuing on from yesterday’s work, let’s look at some more ingredients.

part 1 | part 2 | part 3 | part 4 | part 5

From the FDA: “Each 0.5-mL dose of the vaccine contains approximately 225 mcg of aluminum (as Amorphous Aluminum Hydroxyphosphate Sulfate adjuvant), 9.56 mg of sodium chloride, 0.78 mg of L-histidine, 50 mcg of polysorbate 80, 35 mcg of sodium borate, <7 mcg yeast protein/dose, and water for injection.“.

Sodium Chloride

This is common salt. Taken on their own, the chemicals are incredibly dangerous, and yet we put it on our food every day.

Chlorine is a poisonous gas. It was used in the second battle of Ypres in World War One, killing up to 1400 people.

And yet when combined with water, it is anti-septic. Chlorine is used to clean swimming pools and drinking water.

In the body, chlorine is necessary in order to produce stomach acid. Avoiding chlorine leads to cerebral dehydration, causing headaches. Despite it being a poisonous gas, you need it in your body.

Sodium is an explosive metal. If you put little bits of sodium into water, it will first fizz, then catch fire, and then explode. I have had the pleasure of knowing what it feels like to have a lump of burning sodium explode out of a glass of water and burn into my scalp. With a big enough lump (a few cm cubed), you can crack a toilet bowl by dropping the lump in, then flushing. Again, I know this from experience.

And yet sodium is required by the body. With too little sodium, your nerves will start to fail leading to muscle weakness, and you have a higher risk of heart attack, stroke, and generally just dying.

With too much sodium, you get hypertension, which causes 7.6 million deaths a year.

When combined, sodium and chlorine form rock-salt, which is the most common way for humans to fulfil their daily sodium and chlorine nutritional needs.

The US government recommends 2.3mg of sodium a day. There’s 9.56mg of sodium chloride in a dose of Gardasil. Taking the relative weights of sodium and chloride into account, there is 3.76mg of sodium in the sodium chloride (9.56/(22.989+35.45)*22.989). That’s 1.63 times your daily recommended intake.

Does that sound scary? One slice of bacon has 180mg of sodium in it. Which is more scary? The one that is 78 times the recommended intake, or the one that is 1.63 times the recommended intake?

The sodium chloride in Gardasil is harmless.

L-histidine

L-histidine (also known as Histidine) is an essential amino acid. It is required by the body, but it cannot be generated by the body.

Histidine is used by the body to create histamine, which is used to induce inflammation during healing. it’s also a pain in the ass when you’re allergic to dust and flowers and who knows what else.

Histidine is a precursor for carnosine, meaning that if you have too little histidine, you can get carnosinemia, which can lead to issues such as hypotonia, developmental delay, mental retardation, degeneration of axons, sensory neuropathy, tremors, demyelinization, gray matter anomalies, myoclonic seizures, and loss of purkinje fibers.

Histidine also translates to diphtamide. A lack of diphtamide leads to a lack of NF-κB. NF-κB is important because it helps to stop premature apotheosis. Without it, your cells self-destruct.

For a more prosaic list of deficiency effects (crappy sex, excema, heart disease), see here.

Too much histidine, and you get constipation. I can’t find a reference indicating exactly how much histidine counts as an overdose, so let’s assume that it’s twice the RDI. that’s a very very conservative estimate.

The RDI for histidine is 10-14mg per 10kg of body weight. 10mg according to the WHO, or 14mg according to the US. I don’t trust the US, so I’ll go with the WHO.

I weigh approximately 70kg, so should take 70mg histidine a day. Let’s say an overdose is 140mg. Gardasil contains 0.78mg.

You would need to have about 180 Gardasil injections all in the same day in order to get a reaction from the histidine.

Tomorrow, I’ll look at polysorbate 80 and sodium borate

Is Gardasil Dangerous? Part 1

I posted a reply recently to a Facebook-friend’s post that advertised an anti-Gardasil documentary. I got a blistering reply, which I’ll address over the next few posts.

part 1 | part 2 | part 3 | part 4 | part 5

The first comment was that Gardasil is not the panacea that they (Merck) claim it to be.

Gardasil is a vaccine which helps prevent specific strains of the HPV virus. It is certainly not a panacea (a medicine that cures all diseases and illnesses), and no-one claims that it is. It will not cure the common cold, it will not cure rickets, it won’t even cure the HPV that it is designed to prevent. Vaccines are designed to be taken before you get sick, in order to prevent a disease from taking hold. Cures are given after you are already sick. Gardasil is not a cure for anything, and is certainly not a panacea.

The second comment was about the ingredients of the vaccine. This has been hashed and rehashed by site after site, but I’ve never properly looked into the ingredients myself. This should be interesting:

According to Merck’s own documentation, “The ingredients are proteins of HPV Types 6, 11, 16, and 18, amorphous aluminum hydroxyphosphate sulfate, yeast protein, sodium chloride, L-histidine, polysorbate 80, sodium borate, and water for injection.“.

The FDA gives exact measurements per dose: “Each 0.5-mL dose of the vaccine contains approximately 225 mcg of aluminum (as Amorphous Aluminum Hydroxyphosphate Sulfate adjuvant), 9.56 mg of sodium chloride, 0.78 mg of L-histidine, 50 mcg of polysorbate 80, 35 mcg of sodium borate, <7 mcg yeast protein/dose, and water for injection.“.

Amorphous aluminium hydroxyphosphate sulfate

According to the website novaccine.com, aluminium-containing adjuvants (a substance which enhances the body’s immune response to an antigen) can cause nerve death, chronic joint and muscle pain and fatigue, and can allow aluminium to enter the brain (which can lead to Alzheimer’s).

I read four of the five research papers referenced in the page (couldn’t find the 5th in a public site). They either refer to very extreme overdoses of aluminium (thousands of times larger than you would encounter in a vaccine), or they refer to a completely different aluminium compound. They don’t prove what the page implies they prove.

Effects of aluminum on the neurotoxicity of primary cultured neurons and on the aggregation of beta-amyloid protein. This research paper says that no adverse effects to neurons were found until they directly exposed a rat brain to 50 μM aluminium-chloride over three weeks. The molecular weight of aluminium chloride is 133.341 g/mol, so 50 μM weighs 0.0067g. The Gardasil injection contains .0002g of amorphous aluminium hydroxyphosphate sulfate. That’s 30 times less, and it is not applied to the brain either, and it’s not applied constantly over three weeks. Also, a rat brain is 2g vs a human brain’s 1300g (650 times heavier). In a human, therefore, you would need to apply 4.3g of aluminium chloride to have the same effect. Gardasil’s aluminium payload is 21,500 times smaller than that.

Aluminium-adjuvanted vaccines transiently increase aluminium levels in murine brain tissue. This research paper is not publicly available, so I can’t comment on it or believe anything anyone says about it.

Determination of Aluminum Levels in the Kidney, Liver, and Brain of Mice Treated with Aluminum Hydroxide. This paper records the results of putting aluminium hydroxide into water drank by mice. After 105 days of drinking the water, the mice were killed and the brains examined with a spectrometer. There was 3.4 times more aluminium in the brains of the mice that drank aluminium for 105 days, than was in the brains of the control mice. The mice drank an average of 5ml of water each day, and the water contained 4μg per ml. So the mice ingested 20μg of aluminium every day for 105 days. The human brain is 650 times heavier than a mouse, so in order to increase the human brain’s aluminium content to 3.4 times normal, a person would need to ingest 0.013g of aluminium per day for 105 days. Gardisil contains 0.0002g. Assuming parity between ingesting/injection and the different aluminium compounds, you would need 6825 injections of Gardasil to get the same effect on the brain.

Macrophagic myofasciitis lesions assess long-term persistence of vaccine-derived aluminium hydroxide in muscle. This one is interesting – it appears to show that in all cases, macrophagic myofasciitis (a disease that is so rare, that it has only ever been observed in France) is caused by aluminium hydroxide adjuvants getting “stuck” under the skin and causing a steady immune response. The paper specifically states that the macrophages were aluminium oxyhydroxide, and not aluminium phosphate. It also specifically states that the particular adjuvant responsible here is likely HBV, HAV, or TT. Not Gardasil. A later paper (2014) by the same author reiterates that it is aluminium hydroxide in particular that causes the reaction, not the hydrophosphate adjuvant.

Macrophagic myofasciitis associated with vaccine-derived aluminium – that’s not a research paper…

What is an adjuvant

Adjuvants are used to make the body have a stronger reaction to a perceived threat. In a vaccination, a dead or disarmed version of the disease is injected into the body. The adjuvant acts to increase the body’s awareness of the intruder, making it easier for the immune system to learn how to destroy it.

Adjuvants were invented in 1920 when Gaston Ramone, a French vet, realised that horses with absesses around the injection site of a vaccine developed better defenses against the diseases being treated against (diphteria and tentanus). He replicated this by inducing absesses in other horses by injecting breadcrumbs and tapioca at the site of the vaccine injection. This had the effect of putting the body’s immune system’s full attention at that point, so the foreign objects were handled and the vaccine payload was more likely to be recognised and addressed as well. Around the same time, in London, doctor Alexander Glenny made a similar discovery with aluminium salts.

Aluminium was first used in human vaccines in 1932, and was the sole adjuvant in use in vaccines until 1992, when the first licensed vaccine to use a non-aluminium adjuvant was invented – a hepatitis A vaccine using a virusome system. Virusomes are spherical lipid layers with influenza markers embedded in the surface to trigger an immune response. Since then, another 6 adjuvants have been used in licensed vaccines, with the most common being an oil-in-water one.

Specific to the aluminium compounds mentioned in the novaccine.com webpage, aluminium hydroxide is used in the vaccine Cervarix, but Gardasil does not use it. Gardasil uses amorphous aluminium hydrophosphate sulphate. There are huge differences between the two compounds. For example, particles of the hydroxide are 100nm in diameter, while the hydrophosphate is 50nm in diameter. The hydroxide can cause MMF in rare cases. the hydrophosphate doesn’t.

No meta-studies have been done which determine whether a aluminium adjuvants on average increases all-cause mortality risk, however a group of scientists are planning that research. Until the results are released, if anyone says that aluminium-based adjuvants are bad, they are not using science, or they are cherry-picking.

yeast protein

I’m not sure why yeast protein would be a bad thing, but let’s look into it.

A fascinating paper from 1919 says that if you feed rats a pure yeast diet for a year (nothing else), they usually become infertile.

I suppose the equivalent in humans would be if you were eat just Marmite and nothing else. If any Australians are reading, please tell me if you have any kids…

Merck uses yeast protein during the production of Gardasil, however by the time the vaccine is ready for injection, it contains less than 7μg. In Marmite terms, the yeast protein in one teaspoon of Marmite is the equivalent of 950,000 doses of Gardasil.
(Marmite has a density of 1330kg/m3 or 1.33g/ml, one teaspoon holds 5ml. 5*1.33/7e-6 = 950,000)

Read on to the next set of ingredients.

FOXO4 DRI prices, September 2018

It’s been a while (a year!) since I checked these, and finally there appears to be some movement in the prices.

Bucky Labs dropped their prices right down to about $450 for 30mg of FOXO4 DRI. That’s incredibly low. Suspiciously low? Your mileage may vary. With the expense of these peptides, if you do buy some, have it tested to ensure it is what you paid for.

NovoPro’s price hasn’t budged in the whole year since I checked last, staying at $1756.8 for 30mg. At a guess, this is because FOXO4 DRI is still not a trend, so there isn’t enough demand that would help reduce prices through mass-manufacture.

LookChem (new) are advertising at $100 per milligram, making their price $3000 for 30mg (our comparison base).

Austropeptide (new) is at $600 per 5mg, so $3600 for $30mg.

YoungShe doesn’t appear to be selling the FOXO4-DRI peptide anymore.

Breakthrough BioLabs can sell FOXO4-DRI at a price of $336 per 30mg!

Again, a warning that if you purchase chemicals online, you must get them checked at a local lab to see that they are what you wanted.

The lowest price I can find this month is Breakthrough Biolabs’ $336 for 30mg.

Shop 2017 Sep 2018 Sep
333.6
Bucky Labs 2265 450
NovoPro 1756.8 1756.8
LookChem 3000
AustroPeptide 3600